RELAXIN-CHIMERIC POLYPEPTIDES AND THEIR PREPARATION AND USE

Chimeric polypeptides of relaxin-3, pre­propolypeptides thereof, polynucleotides encoding such polypeptides, and associated expression vectors and host cells are described. The polypeptides may be used to prepare receptor-ligand complexes with GPCR135 or GPCR142, which may be used in assay methods....

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Main Authors LOVENBERG, TIMOTHY, W, KUEI, CHESTER, BONAVENTURE, PASCAL, LIU, CHANGLU, SUTTON, STEVEN, W
Format Patent
LanguageEnglish
French
Published 09.03.2006
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Chimeric polypeptides of relaxin-3, pre­propolypeptides thereof, polynucleotides encoding such polypeptides, and associated expression vectors and host cells are described. The polypeptides may be used to prepare receptor-ligand complexes with GPCR135 or GPCR142, which may be used in assay methods. Polypeptides chimères de relaxine-3, leurs pré-propolypeptides, polynucléotides codant de tels polypeptides et vecteurs d'expression associés ainsi que cellules hôtes. Les polypeptides servent à préparer des complexes récepteur-ligand avec GPCR135 ou GPCR142 que l'on utilise dans des procédés d'essai.
Bibliography:Application Number: WO2005US30257