SUBTYPE OF HUMANIZED ANTIBODY AGAINST INTERLEUKIN-6 RECEPTOR

• Main Authors: KANO, KATSUHIRO, TERASHIMA, ISAMU
• Format: Patent
• Language: English; French; Japanese
• Published: 29.09.2005
• Edition: 7
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

As a subtype of humanized PM-1 antibody against interleukin-6 receptor (IL-6R), there is provided antibody subtype (1) whose one heavy chain C terminus consists of Pro-NH2 (447). As another subtype of humanized PM-1 antibody against interleukin-6 receptor (IL-6R), there is provided antibody subtype (2) whose both heavy chain C termini consist of Pro-NH2 (447). Furthermore, there are provided pharmaceutical compositions comprising these. Comme sous-type d'anticorps anti-PM-1 humanisé contre un récepteur de l'interleukine-6 (IL-6R), il est fourni un sous-type d'anticorps (1) dont une terminaison C de la chaîne lourde est constituée de Pro-NH2 (447). Comme autre sous-type d'anticorps anti-PM-1 humanisé contre un récepteur de l'interleukine-6 (IL-6R), il est fourni un sous-type d'anticorps (2) dont les deux terminaisons C de la chaîne lourde sont constituées de Pro-NH2 (447). En outre, il est fourni des compositions pharmaceutiques comprenant ceux-ci.