PHOSPHOLIPASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM

• Main Authors: LAM, DAVID, ISAAC, CHARLES, BURK, MARK, J, HAZLEWOOD, GEOFF, VASAVADA, AMIT, GRAMATIKOVA, SVETLANA, VAN HOEK, WILHELMUS, P, JANSSEN, GISELLE, ROBERTSON, DAN, E, FIELDING, RODERICK, BADILLO, ADRIAN, KREPS, JOEL, A, BROWN, ROBERT, C, STURGIS, BLAKE, G, BARTON, NELSON, R, LI, JINCAI, TAN, XUQIU
• Format: Patent
• Language: English; French
• Published: 02.04.2009
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; DERIVATIVES THEREOF; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; NUCLEIC ACIDS; NUCLEOSIDES; NUCLEOTIDES; ORGANIC CHEMISTRY; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; SUGARS; VINEGAR; WINE

The invention provides novel polypeptides having phospholipase activity, including, e.g., phospholipase A, B, C and D activity, patatin activity, phosphatidic acid phosphatases (PAP)) and/or lipid acyl hydrolase (LAH) activity, nucleic acids encoding them and antibodies that bind to them. Industrial methods, e.g., oil degumming, and products comprising use of these phospholipases are also provided. L'invention concerne de nouveaux polypeptides présentant une activité de phospholipidase, notamment une activité de phospholipidase A, B, C et D, l'activité de patatine, une activité d'acide phosphatidique phosphatases (PAP) et/ou de d'acide lipidique hydrolase (LAH), des acides nucléiques codant ceux-ci et des anticorps qui se lient auxdits polypeptides. L'invention concerne également des procédés industriels, par exemple, la démucilagination de l'huile, et des produits comprenant l'utilisation desdites phospholipidases.