PROCESS FOR THE PREPARATION OF CABERGOLINE

A process for preparing cabergoline (I) from ergoline-8ß-carboxylic acid ester (XIII) comprising the following steps. (XIII), (XVI), (XVII), (XVIII), (XIX), (I). The present case also relates to the intermediates (XVI), (XVII), (XVIII) and (XIX) as well as the polymorphic amorphous form of Cabergoli...

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Main Authors BALINT, SANDORNE, KASSAI, FERENCNE, SEBOK, FERENC, DEMETER, ADAM, CZIBULA, LASZLO, GALAMBOS, JANOS, IGNACZNE SZENDREI, GYOERGYI
Format Patent
LanguageEnglish
French
Published 06.04.2006
Edition7
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Summary:A process for preparing cabergoline (I) from ergoline-8ß-carboxylic acid ester (XIII) comprising the following steps. (XIII), (XVI), (XVII), (XVIII), (XIX), (I). The present case also relates to the intermediates (XVI), (XVII), (XVIII) and (XIX) as well as the polymorphic amorphous form of Cabergoline (I) and the production thereof. L'invention concerne un procédé de préparation de la cabergoline (I) à partir de l'ester d'acide ergoline-8ß-carboxylique (XIII), qui consiste (a) à faire réagir un ester d'acide ergoline-8ß-carboxylique de formule (XIII), dans laquelle R<sub
Bibliography:Application Number: WO2005HU00022