SALT AND CRYSTALLINE FORM THEREOF OF A CORTICOTROPIN RELEASING FACTOR RECEPTOR ANTAGONIST

The present invention provides 4-(bis(2-methoxyethyl)amino)-2,7-dimethyl-8-(2-methyl-4-methoxyphenyl)-[1,5-a)-pyrazolo-1,3,5-triazine benzenesulfonate salt and a crystalline polymorph thereof Further provided are pharmaceutical compositions containing the salt and methods of treating CRF-related dis...

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Bibliographic Details
Main Authors MEENAN, PAUL, A, RILEY, SHELLEY, RABEL, R, GILLIGAN, PAUL, J
Format Patent
LanguageEnglish
French
Published 09.06.2005
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The present invention provides 4-(bis(2-methoxyethyl)amino)-2,7-dimethyl-8-(2-methyl-4-methoxyphenyl)-[1,5-a)-pyrazolo-1,3,5-triazine benzenesulfonate salt and a crystalline polymorph thereof Further provided are pharmaceutical compositions containing the salt and methods of treating CRF-related disorders using said salt. La présente invention à pour objet un sel de benzène sulfonate 4-(bis(2-méthoxyéthyl)amino)-2,7-diméthyl-8-(2-méthyl-4-méthoxyphényl)-[1,5-a)-pyrazolo-1,3,5-triazineet son polymorphe cristallin. L'invention à également pour objet des compositions pharmaceutiques contenant les sels et des méthodes de traitement de troubles associés à la corticolibérine utilisant ledit sel.
Bibliography:Application Number: WO2004US38948