A PROCESS FOR PURIFICATION

The present invention provides a process for purification of pharmaceutically active compounds selected from the group consisting of thiazolidinedione derivatives and trans-3-Ethyl-2,5-dihydro-4-methyl-N- [2-[4-[[[(4-methylcyclohexyl)amino] carbonyl] amino]sulfonyl]phenyl]ethyl]-2-oxo-1H-pyrrole-1-c...

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Bibliographic Details
Main Authors THENNATI, RAJAMANNAR, REHANI, RAJEEV BUDHDEV, CHHABADA, VIJAY CHHANGAMAL, PANDYA, RASHMINKUMAR RAMESHCHANDRA
Format Patent
LanguageEnglish
French
Published 02.06.2005
Edition7
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The present invention provides a process for purification of pharmaceutically active compounds selected from the group consisting of thiazolidinedione derivatives and trans-3-Ethyl-2,5-dihydro-4-methyl-N- [2-[4-[[[(4-methylcyclohexyl)amino] carbonyl] amino]sulfonyl]phenyl]ethyl]-2-oxo-1H-pyrrole-1-carboxamide comprising extraction in a solvent comprising an alkanol (C1-C4) and ammonia. La présente invention concerne un procédé de purification de composés pharmaceutiquement actifs pris dans le groupe composé de dérivés de thiazolidinedione et de trans -3-éthyl-2,5-dihydro-4-méthyl-N- [2-[4-[[[(4-méthylcyclohexyl)amino] carbonyl] amino]sulfonyl]phényl]éthyl]-2-oxo-1H-pyrrole-1-carboxamide, consistant à extraire un solvant comprenant un alcanol (C1-C4) et d l'ammoniac.
Bibliography:Application Number: WO2004IN00298