NOVEL COMPOUNDS AND THEIR USE IN THERAPY

This invention relates to novel thiophenepyrimidinone derivatives and their use in therapy, especially for use in the treatment and/or prevention of a steroid hormone de­pendent diseases or disorder, such as steroid hormone dependent diseases or disorders requiring inhibition of 17ß-hydroxysteroid d...

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Main Authors HIRVELAE, LEENA, KOSKIMIES, PASI, PENTIKAEINEN, OLLI TANELI, NYROENEN, TOMMI, SALMINEN, TIINA ANNAMARIA, JOHNSON, MARK STUART, JOHANSSON, NINA
Format Patent
LanguageEnglish
French
Published 14.04.2005
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:This invention relates to novel thiophenepyrimidinone derivatives and their use in therapy, especially for use in the treatment and/or prevention of a steroid hormone de­pendent diseases or disorder, such as steroid hormone dependent diseases or disorders requiring inhibition of 17ß-hydroxysteroid dehydrogenase enzymes. Cette invention se rapporte à de nouveaux dérivés thiophènepyrimidinone et à leur utilisation en thérapie, notamment dans le traitement et/ou la prévention des maladies ou des troubles dépendant de l'hormone stéroïde, tels que les maladies ou les troubles dépendant de l'hormone stéroïde nécessitant l'inhibition des enzymes 17ss-hydroxystéroïdr-déshydrogénases.
Bibliography:Application Number: WO2004EP06230