NANOPARTICLE CONJUGATES AND METHOD OF PRODUCTION THEREOF

The present invention relates to a nanoparticle conjugate comprising a nanoparticle conjugated to a plurality of peptides of a substantially similar amino acid sequence, a peptide conjugated to the nanoparticle by means of a Cysteine (C) residue and the nanoparticle conjugate further comprising a li...

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Bibliographic Details
Main Authors FERNIG, DAVID, GARTH, LEVY, RAPHAEL, DOTY, RICHARD, CHRISTOPHER, THANH, DGUYEN, THI, KIM, SMITH, JOHN, ARTHUR
Format Patent
LanguageEnglish
French
Published 15.09.2005
Edition7
Subjects
CHEMISTRY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES
MEASURING
METALLURGY
NANOTECHNOLOGY
ORGANIC CHEMISTRY
PEPTIDES
PERFORMING OPERATIONS
PHYSICS
SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES
TESTING
TRANSPORTING
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Summary:The present invention relates to a nanoparticle conjugate comprising a nanoparticle conjugated to a plurality of peptides of a substantially similar amino acid sequence, a peptide conjugated to the nanoparticle by means of a Cysteine (C) residue and the nanoparticle conjugate further comprising a ligand attached to the peptide and additionally an identification means. The present invention also relates to method of producing the nanoparticle conjugate. L'invention concerne des conjugués de nanoparticules comprenant une nanoparticule conjuguée à une pluralité de peptides d'une séquence d'aminoacides sensiblement similaires, un peptide conjugué à une nanoparticule au moyen d'un reste de cystéine (C). Le conjugué de nanoparticules comprend, de plus, un liant fixé au peptide et éventuellement des moyens d'identification. L'invention concerne, en outre, un procédé pour produire le conjugué de nanoparticules de l'invention.
Bibliography:Application Number: WO2004GB03986