CYTOKINE INHIBITORS

The present invention provides low molecular weight compounds useful as cytokine inhibitors, and compositions thereof. In particular, compounds of the invention are useful as anti-inflammatory agents. There are further provided methods for the preparation of such agents and their use in preventing o...

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Main Authors SAIAH, EDDINE, DELAET, NANCY, G., J, ROBERTS, EDWARD, NAKANISHI, HIROSHI, ERNST, JUSTIN, KAHL, JEFFREY, D, BOMAN, ERIK, DAHL, RUSSELL, MONTALBAN, ANTONIO, G, MILLER, STEPHEN, CEIDE, SUSANA, C, SULLIVAN, ROBERT, WANG, ZHIJUN, LARSON, CHRISTOPHER
Format Patent
LanguageEnglish
French
Published 14.07.2005
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention provides low molecular weight compounds useful as cytokine inhibitors, and compositions thereof. In particular, compounds of the invention are useful as anti-inflammatory agents. There are further provided methods for the preparation of such agents and their use in preventing or treating conditions mediated by cytokines such as arthritis. L'invention concerne des composés à faible poids moléculaire, utilisés en tant qu'inhibiteurs des cytokines, ainsi que des compositions associées. Les composés selon l'invention sont particulièrement utiles en tant qu'agents anti-inflammatoires. L'invention concerne également des procédés de préparation desdits agents, ainsi que leur utilisation dans la prévention ou le traitement d'états induits par les cytokines, tels que l'arthrite.
Bibliography:Application Number: WO2004US29372