AMINOPIPERIDINE AMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF

Compounds of formula (I) that are VLA-1 integrin antagonists are disclosed. Also disclosed are compositions containing such compounds and methods of using such compounds in treating diseases mediated, at least in part, by the VLA-1 integrin. L'invention concerne des composés de formule générale...

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Main Authors DEMEESE, JASON, LEHUEROU, YVAN, ZHANG, GAN, BOYD, STEVEN, A, GUNAWARDANA, INDRANI, XU, RUI, YANIK, MATTHEW, MILLER, SCOTT, THORSETT, EUGENE, THOMAS, ALLEN, MCLAUGHLIN, MARTIN, LUPHER, MARK, L., JR, JACOBSON, IRINA, C
Format Patent
LanguageEnglish
French
Published 03.03.2005
Edition7
Subjects
ARTIFICIAL STONE
CEMENTS
CERAMICS
CHEMISTRY
COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDINGMATERIALS
CONCRETE
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
LIME, MAGNESIA
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
REFRACTORIES
SLAG
TREATMENT OF NATURAL STONE
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Summary:Compounds of formula (I) that are VLA-1 integrin antagonists are disclosed. Also disclosed are compositions containing such compounds and methods of using such compounds in treating diseases mediated, at least in part, by the VLA-1 integrin. L'invention concerne des composés de formule générale (I) qui sont des antagonistes d'intégrine VLA-1. L'invention concerne également des compositions contenant lesdits composés et des procédés d'utilisation de ceux-ci dans le traitement de maladies dont la médiation est assurée, au moins en partie, par l'intégrine VLA-1.
Bibliography:Application Number: WO2004US26207