METHOD OF PURIFYING MACROLIDES

Provided is a method of purifying a macrolide, especially tacrolimus, that includes loading macrolide onto a bed of sorption resin and elting with a suitable eluent such as a combination of water and tetrahydrofuran. L'invention concerne un procédé de purification d'un macrolide, en partic...

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Bibliographic Details
Main Authors CZOVEK, ZOLTAN, CSORVASI, ANDREA, RANTAL, FERENC, KERI, VILMOS
Format Patent
LanguageEnglish
French
Published 17.03.2005
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Provided is a method of purifying a macrolide, especially tacrolimus, that includes loading macrolide onto a bed of sorption resin and elting with a suitable eluent such as a combination of water and tetrahydrofuran. L'invention concerne un procédé de purification d'un macrolide, en particulier le tacrolimus, qui consiste à charger le macrolide sur un lit de sorption et à procéder à son élution au moyen d'un éluant approprié de type combinaison d'eau et de tétrahydrofurane.
Bibliography:Application Number: WO2004US24318