CYCLIC TERTIARY AMINE COMPOUND

A cyclic tertiary amine compound which is capable of inhibiting the production of inflammatory cytokine. It is either a compound having a structure represented by the following general formula (I): (I) (wherein A represents an optionally substituted trivalent group derived from pyrimidine, pyrrole,...

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Bibliographic Details
Main Authors SHIMOZATO, TAKAICHI, NAKAO, AKIRA, NAGASAKI, TAKAYOSHI, KIMURA, TOMIO, OHKAWA, NOBUYUKI
Format Patent
LanguageEnglish
French
Japanese
Published 23.12.2004
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A cyclic tertiary amine compound which is capable of inhibiting the production of inflammatory cytokine. It is either a compound having a structure represented by the following general formula (I): (I) (wherein A represents an optionally substituted trivalent group derived from pyrimidine, pyrrole, or the like; R represents optionally substituted aryl or heteroaryl; R represents optionally substituted heteroaryl; and R represents cyclic tertiary amino) or a pharmacologically acceptable salt of the compound. L'invention concerne un composé d'amine tertiaire cyclique permettant d'inhiber la production de cytokine inflammatoire. Il consiste soit en un composé possédant une structure représentée par la formule générale (I), dans laquelle A représente un groupe trivalent éventuellement substitué dérivé de pyrimidine, pyrrole ou analogue; R représente un aryle ou un hétéroaryle éventuellement substitué; R représente un hétéroaryle éventuellement substitué; et R représente un amino tertiaire cyclique; soit en un sel acceptable sur la plan pharmacologique de ce composé.
Bibliography:Application Number: WO2004JP08492