FUSION PROTEINS FOR THE TREATMENT OF CNS

This disclosure relates to compositions capable of use in the treatment of spinal cord injuries and related disorders of the central nervous system (CNS), and in particular, compositions including proteoglycan degrading molecules and compositions capable of blocking and/or over coming the activity o...

Full description

Saved in:
Bibliographic Details
Main Authors CAGGIANO, ANTHONY, O, ROY, GARGI, GRUSKIN, ELLIOTT, A, ZIMBER, MICHAEL, P, IACI, JENNIFER
Format Patent
LanguageEnglish
French
Published 16.02.2006
Edition7
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

More Information
Summary:This disclosure relates to compositions capable of use in the treatment of spinal cord injuries and related disorders of the central nervous system (CNS), and in particular, compositions including proteoglycan degrading molecules and compositions capable of blocking and/or over coming the activity of neuronal growth inhibitory molecules, as well as fusion proteins which includes a proteoglycan degrading domain and a domain capable of blocking and or over coming the activity of neuronal growth inhibitory molecules. L'invention concerne des compositions pouvant être utilisées dans le traitement de lésions de la moelle épinière et de troubles associés du système nerveux central (SNC), et plus particulièrement des compositions comprenant des molécules de dégradation du protéoglycane et des compositions permettant de bloquer et/ou de supprimer l'activité de molécules inhibitrices de la croissance neuronale, ainsi que des protéines de fusion renfermant un domaine de dégradation du protéoglycane et un domaine permettant de bloquer et/ou de supprimer l'activité de molécules inhibitrices de la croissance neuronale.
Bibliography:Application Number: WO2004US15661