THERAPEUTIC POLYPEPTIDES, NUCLEIC ACIDS ENCODING SAME, AND METHODS OF USE

• Main Authors: MALYANKAR, URIEL, M, ZHONG, MEI, VERNET, CORINE, A., M, GUO, XIAOJIA, PATTURAJAN, MEERA, CASMAN, STACIE, J, ANDERSON, DAVID, W, LI, LI, PADIGARU, MURALIDHARA, BOLDOG, FERENC, L, KEKUDA, RAMESH, KHRAMTSOV, NIKOLAI, V, MILLER, CHARLES, E
• Format: Patent
• Language: English; French
• Published: 21.09.2006
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPOSITIONS THEREOF; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; CULTURE MEDIA; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; HUMAN NECESSITIES; HYGIENE; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROCESSES OF PREPARING SUCH COMPOSITIONS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins. Cette invention concerne des séquences d'acides nucléiques qui codent de nouveaux polypeptides, les polypeptides codés par ces séquences d'acides nucléiques, et des anticorps qui se fixent en mode immunospécifique à ces polypeptides, ainsi que des dérivés, des variants, des mutants ou des fragments de ces nouveaux polypeptides, de ces polynucléotides ou de ces anticorps spécifiques de ces polypeptides. Cette invention concerne en outre des procédés thérapeutiques, diagnostiques et de recherche pour le diagnostic, le traitement et la prévention des troubles impliquant l'un ou l'autre de ces nouveaux acides nucléiques ou protéines humains.