NOVEL PURIFIED PHOSPHODIESTERASE POLYPEPTIDES

The present invention relates to novel compositions of phosphodiesterase polypeptides. Accordingly, the invention provides purified protein comprising the amino acid sequence set forth in SEQ ID NOs: 2, 11, and/or 38, and fragments thereof. The invention also provides biochemical and biophysical cha...

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Main Authors MENDLEIN, JOHN, D, WANG, PEIXIANG, DOMAGALA, MEGAN, PAN, JAMES, GUOHUA, DHARAMSI, AKIL, MAMELAK, DANIEL, MCDONALD, MERRY-LYNN
Format Patent
LanguageEnglish
French
Published 19.08.2004
Edition7
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Summary:The present invention relates to novel compositions of phosphodiesterase polypeptides. Accordingly, the invention provides purified protein comprising the amino acid sequence set forth in SEQ ID NOs: 2, 11, and/or 38, and fragments thereof. The invention also provides biochemical and biophysical characteristics of the polypeptides of the invention. La présente invention concerne des nouvelles compositions de polypeptides de phosphodiestérase,. Ainsi, cette invention porte sur une protéine purifiée renfermant la séquence d'acides aminés décrites dans SEQ ID NOs: 2, 11, et/ou 38, ainsi que des fragments de ces séquences. Sont également décrites les caractéristiques biochimiques et physiques des polypeptides de l'invention.
Bibliography:Application Number: WO2004CA00167