METHOD OF SCREENING AGENT FOR IMPROVING MEMORY AND LEARNING ABILITY

A screening tool and a screening method for obtaining a substance which is useful as a memory improving agent, a learning ability improving agent and/or an antidementia agent; a polypeptide, a polynucleotide, a vector and cells which are usable in the above screening; and a novel memory improving ag...

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Bibliographic Details
Main Authors INAMURA, KOHEI, SANO, YORIKATA, MOCHIZUKI, SHINOBU
Format Patent
LanguageEnglish
French
Japanese
Published 05.08.2004
Edition7
Subjects
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Summary:A screening tool and a screening method for obtaining a substance which is useful as a memory improving agent, a learning ability improving agent and/or an antidementia agent; a polypeptide, a polynucleotide, a vector and cells which are usable in the above screening; and a novel memory improving agent, a learning ability improving agent and/or an antidementia. The screening tool as described above comprises a calcium-permeable nonselective cation channel or cells expressing the same. Un outil de criblage et un procédé de criblage servent à obtenir une substance qui est utile en tant qu'agent améliorant la mémoire, un agent améliorant la capacité d'apprentissage et/ou un agent dirigé contre la démence; un polypeptide, un polynucléotide, un vecteur et des cellules qui peuvent s'utiliser dans ces procédés de criblage, et un nouvel agent améliorant la mémoire, un agent améliorant la capacité d'apprentissage et/ou un agent dirigé contre la démence. L'outil de criblage décrit ci-dessus comprend un canal de calcium non sélectif perméable au calcium ou des cellules qui l'expriment.
Bibliography:Application Number: WO2004JP00333