ALKYL-LINKED NUCLEOTIDE COMPOSITIONS

Alkyl-linked nucleotide compositions and nucleotide affinity media comprising an alkyl-linked nucleotide are provided. The linker is generally a hydrophobic linker that can be a 3, 4, 5, 6, 7, 8, 9, 10, or a longer carbon chain. Also included in the invention are methods for synthesis of an alkyl-li...

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Bibliographic Details
Main Authors HARDEMAN, KLASS, P, HALL, STEVEN, E, JENKS, MATTHEW, G, HINKLEY, LINDSAY, A, WARE, ROY, W
Format Patent
LanguageEnglish
French
Published 05.08.2004
Edition7
Subjects
CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY
CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
SEPARATION
SUGARS
THEIR RELEVANT APPARATUS
TRANSPORTING
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Summary:Alkyl-linked nucleotide compositions and nucleotide affinity media comprising an alkyl-linked nucleotide are provided. The linker is generally a hydrophobic linker that can be a 3, 4, 5, 6, 7, 8, 9, 10, or a longer carbon chain. Also included in the invention are methods for synthesis of an alkyl-linked nucleotide, nucleotide affinity media and methods of use thereof for affinity chromatography and screening methods. L'invention concerne des compositions de nucléotides à liaison alkyl et des substances à affinité pour les nucléotides contenant des nucléotides à liaison alkyl. Le lieur est générallement un lieur hydrophobe pouvant être une chaîne portant 3, 4, 5, 6, 7, 8, 9 ou 10 atomes de carbone ou plus. L'invention concerne également des procédés de synthèse d'un nucléotide à liaison alkyl, des substances à affinité pour les nucléotides, et des procédés d'utilisation de ceux-ci dans la chromatographie par affinité et des procédés de criblage.
Bibliography:Application Number: WO2004US01745