NITROFURANTOIN CONTROLLED RELEASE DOSAGE FORM

The present invention generally relates to controlled release dosage forms which provide immediate release and sustained release of nitrofurantoin, and processes for their preparation. The controlled release dosage form includes a sustained release portion and an immediate release portion. The susta...

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Bibliographic Details
Main Authors NAGAPRASAD, VISHNUBHOTLA, MALIK, RAJIV, KUMAR, PANANCHUKUNNATH, MANOJ, SHARMA, PUNEET, ROY, SUNILENDU, BHUSHAN
Format Patent
LanguageEnglish
French
Published 13.05.2004
Edition7
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention generally relates to controlled release dosage forms which provide immediate release and sustained release of nitrofurantoin, and processes for their preparation. The controlled release dosage form includes a sustained release portion and an immediate release portion. The sustained release portion includes nitrofurantoin and one or more pH dependent hydrophilic polymers. The immediate release portion includes nitrofurantoin. L'invention concerne des formes galéniques à libération contrôlée permettant de libérer nitrofurantoïne de façon immédiate et prolongée, ainsi que des méthodes servant à les préparer. Cette forme galénique contient une partie de libération prolongée et une partie de libération immédiate. La partie de libération prolongée contient nitrofurantoïne et un ou plusieurs polymères hydrophiles dépendant du pH. La partie de libération immédiate contient nitrofurantoïne.
Bibliography:Application Number: WO2003IB03517