THERAPEUTIC COMPOUNDS FOR TREATING DYSLIPIDEMIC CONDITIONS

The present invention relates to novel LXR ligands of Formula I and the pharmaceutically acceptable salts, esters and tautomers thereof, which are useful in the treatment of dyslipidemic conditions, particularly depressed levels of HDL cholesterol. La présente invention concerne de nouveaux ligands...

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Main Authors TSE, BRUNO, GREEN, AHREN, I, ADAMS, ALAN, D, HUANG, SHAEI, Y, JONES, A., BRIAN, GUTTERIDGE, CLARE, E, CHENG, YUAN
Format Patent
LanguageEnglish
French
Published 05.02.2004
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention relates to novel LXR ligands of Formula I and the pharmaceutically acceptable salts, esters and tautomers thereof, which are useful in the treatment of dyslipidemic conditions, particularly depressed levels of HDL cholesterol. La présente invention concerne de nouveaux ligands LXR de formule (I) et les sels, esters et tautomères pharmaceutiquement acceptables de ces ligands, qui présentent une utilité dans le traitement d'états dyslipidémiques, en particulier de taux abaissés de cholestérol HDL.
Bibliography:Application Number: WO2003US22807