MULTIMERISED GROWTH HORMONE FUSION PROTEINS
The present invention relates to multimerised growth hormone polypeptides wherein growth hormone is fused with a multimerisation domain, such as a tetranectin trimerising structural element. Thereby there is provided growth hormone multimers, e.g. growth hormone dimers and growth hormone trimers, wi...
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| Main Author | |
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| Format | Patent |
| Language | English French |
| Published |
15.01.2004
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| Edition | 7 |
| Subjects | |
| Online Access | Get full text |
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| Abstract | The present invention relates to multimerised growth hormone polypeptides wherein growth hormone is fused with a multimerisation domain, such as a tetranectin trimerising structural element. Thereby there is provided growth hormone multimers, e.g. growth hormone dimers and growth hormone trimers, with increased biological activity.
La présente invention concerne des polypeptides de l'hormone de croissance multimérisée, l'hormone de croissance étant soudée à un domaine de multimérisation, tel qu'un élément structural trimérisant la tétranectine. Ainsi, on obtient des multimères d'hormone de croissance, p.ex. des dimères d'hormone de croissance et des trimères d'hormone de croissance, ayant une activité biologique accrue. |
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| AbstractList | The present invention relates to multimerised growth hormone polypeptides wherein growth hormone is fused with a multimerisation domain, such as a tetranectin trimerising structural element. Thereby there is provided growth hormone multimers, e.g. growth hormone dimers and growth hormone trimers, with increased biological activity.
La présente invention concerne des polypeptides de l'hormone de croissance multimérisée, l'hormone de croissance étant soudée à un domaine de multimérisation, tel qu'un élément structural trimérisant la tétranectine. Ainsi, on obtient des multimères d'hormone de croissance, p.ex. des dimères d'hormone de croissance et des trimères d'hormone de croissance, ayant une activité biologique accrue. |
| Author | HOLTET, THOR, LAS |
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| DocumentTitleAlternate | HORMONE DE CROISSANCE MULTIMERISEE |
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| RelatedCompanies | BOREAN PHARMA A/S HOLTET, THOR, LAS |
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| Snippet | The present invention relates to multimerised growth hormone polypeptides wherein growth hormone is fused with a multimerisation domain, such as a tetranectin... |
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| SubjectTerms | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| Title | MULTIMERISED GROWTH HORMONE FUSION PROTEINS |
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