3,4-DIHYDROISOQUINOLIN-1-ONE DERIVATIVES AS INDUCERS OF APOPTOSIS

The present invention related to certain 3,4-dihydroisoquinolin-1-ones that are activators of caspases and inducers of apoptosis, pharmaceutical composition comprising these compounds, and method of treating cancer utilizing these compounds. L'invention concerne des dérivés 3,4-dihydroisoquinol...

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Bibliographic Details
Main Authors GANGLOFF, ANTHONY, R, LITVAK, JOANE, PARARAJASINGHAM, KEITH, SPERANDIO, DAVID
Format Patent
LanguageEnglish
French
Published 15.01.2004
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention related to certain 3,4-dihydroisoquinolin-1-ones that are activators of caspases and inducers of apoptosis, pharmaceutical composition comprising these compounds, and method of treating cancer utilizing these compounds. L'invention concerne des dérivés 3,4-dihydroisoquinolin-1-ones qui sont des activateurs de caspases et des inducteurs d'apoptose, une composition pharmaceutique contenant ces composés, ainsi qu'une méthode de traitement du cancer au moyen de ces composés.
Bibliography:Application Number: WO2003US21102