DIAGNOSIS OF ALZHEIMER'S DISEASE BASED ON THE hAbeta42:hAbeta40 RATIO

Described is a method for the diagnosis of Alzheimer's Disease (AD) or of a risk for developing said disease which is based on the determination of the ratio of hAbeta42:hAbeta40 (Abeta42/40-ratio). A lower Abeta42/40-ratio as compared to the normal ratio is indicative for AD or for a risk for...

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Bibliographic Details
Main Authors EIKENBERG, OLIVER, HARTMANN, TOBIAS, ANTZ, CHRISTOF
Format Patent
LanguageEnglish
French
Published 19.02.2004
Edition7
Subjects
CHEMISTRY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
TESTING
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Summary:Described is a method for the diagnosis of Alzheimer's Disease (AD) or of a risk for developing said disease which is based on the determination of the ratio of hAbeta42:hAbeta40 (Abeta42/40-ratio). A lower Abeta42/40-ratio as compared to the normal ratio is indicative for AD or for a risk for developing AD. Moreover, kits are described suitable for carrying out said diagnostic method. L'invention concerne une méthode de diagnostic de la maladie d'Alzheimer ou d'un risque de développer ladite maladie, cette méthode reposant sur la détermination du taux de hA beta 42:hA beta 40 (taux A beta 42/40). Un taux A beta 42/40 inférieur au taux normal révèle la maladie d'Alzheimer ou un risque de la développer. En outre, cette invention a trait à des kits appropriés pour réaliser ladite méthode de diagnostic.
Bibliography:Application Number: WO2003EP05982