SUBSTITUTED PYRROLINES AS KINASE INHIBITORS

The present invention is directed to novel substituted pyrroline compounds of formula (I) useful as kinase or dual-kinase inhibitors, methods for producing such compounds and methods for treating or ameliorating a kinase or dual-kinase mediated disorder. L'invention concerne des composés de pyr...

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Main Authors DEMAREST, KEITH, WHITE, KIMBERLY, HECKER, LEONARD, MARYANOFF, BRUCE E, ZHANG, HANNG, MCCOMSEY, DAVID F, YE, HONG, CONWAY, BRUCE R
Format Patent
LanguageEnglish
French
Published 08.07.2004
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention is directed to novel substituted pyrroline compounds of formula (I) useful as kinase or dual-kinase inhibitors, methods for producing such compounds and methods for treating or ameliorating a kinase or dual-kinase mediated disorder. L'invention concerne des composés de pyrroline substitués utiles comme inhibiteurs de kinase ou de kinase-2, des procédés relatifs à l'élaboration de ces composés, et des procédés relatifs au traitement ou à l'atténuation de troubles dont la médiation est assurée par la kinase ou la kinase-2.
Bibliography:Application Number: WO2003US17518