MODIFIED T LYMPHOCYTES AND USES THEREFOR

Modified T lymphocytes that express a chimeric T cell receptor reactive with two or more different cell surface angiogenic marker are disclosed. The modified T lymphocytes are useful in methods in controlling angiogenesis and in therapeutic methods in controlling tumor growth. L'invention conce...

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Bibliographic Details
Main Authors NIEDERMAN, THOMAS, M., J, GHOGAWALA, ZOHER, MULLIGAN, RICHARD, C, CARTER, BOB, S
Format Patent
LanguageEnglish
French
Published 19.08.2004
Edition7
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
TESTING
VINEGAR
WINE
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Summary:Modified T lymphocytes that express a chimeric T cell receptor reactive with two or more different cell surface angiogenic marker are disclosed. The modified T lymphocytes are useful in methods in controlling angiogenesis and in therapeutic methods in controlling tumor growth. L'invention concerne des lymphocytes T modifiés exprimant un récepteur de cellules T chimères réagissant à deux marqueurs angiogéniques différents de surface cellulaire ou plus. Les lymphocytes T modifiés sont utiles dans des méthodes de maîtrise de l'angiogenèse et dans des méthodes thérapeutiques de lutte contre la croissance tumorale.
Bibliography:Application Number: WO2003US14343