HPPARS ACTIVATORS

Compounds of formula (1) or a pharmaceutically acceptable salt, solvate, acid isostere, or hydrolyzable ester thereof, are disclosed. Methods of making and using the compounds are also disclosed. In particular methods for treating diseases or conditions associated with one or more of human PPAR alph...

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Main Authors LAMBERT, MILLARD, H., III, CADILLA, RODOLFO, SMITH, JENNIFER, SUSAN, LIU, GUANGCHENG, KEVIN, HENKE, BRAD, RICHARD
Format Patent
LanguageEnglish
French
Published 12.09.2003
Edition7
Subjects
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Summary:Compounds of formula (1) or a pharmaceutically acceptable salt, solvate, acid isostere, or hydrolyzable ester thereof, are disclosed. Methods of making and using the compounds are also disclosed. In particular methods for treating diseases or conditions associated with one or more of human PPAR alpha, gamma, or delta ("hPPARs") comprising administration of a therapeutically effective amount of a compound of formula (1), are disclosed. L'invention concerne des composés de formule (1) ou un sel pharmaceutiquement acceptable, un solvate, un isostère acide, ou un ester hydrolysable de ceux-ci. L'invention concerne également des méthodes de fabrication et d'utilisation de ces composés. En particulier, l'invention concerne encore des procédés de traitement de maladies ou de troubles associés à un ou à plusieurs PPAR humains alpha, gamma ou delta ("hPPAR") consistant à administrer une dose thérapeutiquement efficace d'un composé de formule (1).
Bibliography:Application Number: WO2003US05953