NOVEL CYTOKINE ZCYTOR17 LIGAND

• Main Authors: HAMMOND, ANGELA, K, SPRECHER, CINDY, A, KUIJPER, JOSEPH, L, DILLON, STACEY, R, NOVAK, JULIA, E, DASOVICH, MARIA, M, GRANT, FRANCIS, J, GROSS, JANE, A
• Format: Patent
• Language: English; French
• Published: 01.04.2004
• Edition: 7
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPOSITIONS THEREOF; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; CULTURE MEDIA; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; HUMAN NECESSITIES; HYGIENE; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PHYSICS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROCESSES OF PREPARING SUCH COMPOSITIONS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; TESTING; VINEGAR; WINE

The present invention relates to zcytor171ig polynucleotide, polypeptide and anti-zcytor17 antibody molecules. The zcytor171ig is a novel cytokine. The polypeptides may be used within methods for stimulating the immune system, and proliferation and/or development of hematopoietic cells in vitro and in vivo. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto. La présente invention se rapporte à un polynucléotide zcytor17lig, à un polypeptide et à des molécules d'anticorps anti-zcytor17, zcytor17lig étant une nouvelle cytokine. Les polypeptides peuvent être utilisés dans des procédés de stimulation du système immunitaire et de prolifération et/ou de mise au point de cellules hématopoïétiques in vitro et in vivo. La présente invention concerne également des procédés de production de la protéine, ses utilisations et ses anticorps.