PSEUDOMONAS VIRULENCE FACTORS AND USES THEREOF

Disclosed are bacterial virulence polypeptides and nucleic acid sequences (e.g.,DNA) encoding such polypeptides, and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing such polypeptides to screen for antibacterial or bacteriostatic compounds. D...

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Main Authors CALDERWOOD, STEPHEN, B, AUSUBEL, FREDERICK, M, GOUMNERAV, BOYAN, C, RAHME, LAURENCE, G, CHOI, JI YOUNG, SIFRI, COSTI, D
Format Patent
LanguageEnglish
French
Published 17.07.2003
Edition7
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Summary:Disclosed are bacterial virulence polypeptides and nucleic acid sequences (e.g.,DNA) encoding such polypeptides, and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing such polypeptides to screen for antibacterial or bacteriostatic compounds. Disclosed are bacterial virulence polypeptides and nucleic acid sequences e.g.,DNA encoding such polypeptides, and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing such polypeptides to screen for antibacterial or bacteriostatic compounds. L'invention concerne des polypeptides de virulence bactérienne et des séquences nucléotidiques (p. ex. ADN) codant pour ces polypeptides, ainsi que des procédés permettant de produire de tels polypeptides au moyen de techniques de recombinaison. L'invention concerne également des procédés comprenant l'utilisation de ces polypeptides pour l'identification de composés antibactériens ou bactériostatiques.
Bibliography:Application Number: WO2003US00184