THERAPEUTIC POLYPEPTIDES, NUCLEIC ACIDS ENCODING SAME, AND METHODS OF USE

Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polyn...

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Main Authors CASMAN, STACIE, J, EDINGER, SHLOMIT, R, ANDERSON, DAVID, W, DHANABAL, MOHANRAJ, BARON, MELANIE, ALSOBROOK, JOHN, P., II, BURGESS, CATHERINE, E, ALVAREZ, ENRIQUE, BOLDOG, FERENC, L, CHAPOVAL, ANDREI
Format Patent
LanguageEnglish
French
Published 15.05.2003
Edition7
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Summary:Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.. L'invention se rapporte à de nouveaux polypeptides, et aux acides nucléiques les codant, présentant des propriétés de stimulation de réponses biochimiques ou physiologiques dans une cellule, un tissu, un organe ou un organisme. Plus particulièrement, ces nouveaux polypeptides sont des produits géniques de nouveaux gènes, ou des fragments déterminés biologiquement actifs ou des dérivés de ces derniers. L'invention a également trait à des méthodes d'utilisation regroupant des procédés d'analyse diagnostique et pronostique, ainsi qu'à des méthodes de traitement de différentes conditions pathologiques.
Bibliography:Application Number: WO2002US35536