THERAPEUTIC POLYPEPTIDES, NUCLEIC ACIDS ENCODING SAME, AND METHODS OF USE

• Main Authors: CHANT, JOHN, S, EDINGER, SHLOMIT, R, ANDERSON, DAVID, W, ALSOBROOK, JOHN, P., II, BURGESS, CATHERINE, E, GANGOLLI, ESHA, A, EISEN, ANDREW, BOLDOG, FERENC, L, CHAUDHURI, AMITABHA, CHAPOVAL, ANDREI
• Format: Patent
• Language: English; French
• Published: 15.05.2003
• Edition: 7
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPOSITIONS THEREOF; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; CULTURE MEDIA; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; HUMAN NECESSITIES; HYGIENE; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PHYSICS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROCESSES OF PREPARING SUCH COMPOSITIONS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; TESTING; VINEGAR; WINE

Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins. L'invention se rapporte à de nouveaux polypeptides, et à des acides nucléiques les codant, présentant des propriétés de stimulation de réponses biochimiques ou physiologiques dans une cellule, un tissu, un organe ou un organisme. Plus précisément, ces nouveaux polypeptides sont des produits géniques de nouveaux gènes, ou des fragments déterminés biologiquement actifs ou des dérivés de ces derniers. L'invention concerne aussi des méthodes d'utilisation regroupant des procédés d'analyse diagnostique et pronostique, ainsi que des méthodes de traitement de différentes conditions pathologiques.