ANTISENSE MODULATION OF ACTIVATING TRANSCRIPTION FACTOR 3 EXPRESSION

• Main Authors: BAKER, BRENDA, F, DOBIE, KENNETH
• Format: Patent
• Language: English; French
• Published: 15.05.2003
• Edition: 7
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS; TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE; VINEGAR; WINE

Antisense compounds, compositions and methods are provided for modulating the expression of activating transcription factor 3. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding activating transcription factor 3. Methods of using these compounds for modulation of activating transcription factor 3 expression and for treatment of diseases associated with expression of activating transcription factor 3 are provided. La présente invention concerne des composés, des compositions et des procédés antisens qui permettent de moduler l'expression du facteur de transcription activateur 3. Les compositions de l'invention comprennent des composés, en particulier des oligonucléotides antisens, qui ciblent des acides nucléiques codant le facteur de transcription activateur 3. L'invention se rapporte également à des procédés d'utilisation desdits composés pour moduler l'expression du facteur de transcription activateur 3 et pour traiter des maladies associées à l'expression du facteur de transcription activateur 3.