MSREBPs AS MODIFIERS OF THE SREBP PATHWAY AND METHODS OF USE

Human MSREBP genes are identified as modulators of the SREBP pathway and thus are therapeutic targets for disorders associated with the SREBP pathway. Methods for identifying modulators of MSREBP, comprising screening for agents that modulate the activity of MSREBP are provided. L'invention con...

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Bibliographic Details
Main Authors O'BRIEN, CAROL, L, KONG, ERIC, C, KADYK, LISA, C, HAMMONDS, GLENN, R., JR
Format Patent
LanguageEnglish
French
Published 06.11.2003
Edition7
Subjects
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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Summary:Human MSREBP genes are identified as modulators of the SREBP pathway and thus are therapeutic targets for disorders associated with the SREBP pathway. Methods for identifying modulators of MSREBP, comprising screening for agents that modulate the activity of MSREBP are provided. L'invention concerne des gènes MSREBP humains identifiés comme modulateurs de la voie SREBP et constituant des cibles thérapeutiques destinées aux troubles associés à la voie SREBP. L'invention concerne en outre des méthodes destinées à identifier des modulateurs de MSREBP et consistant à rechercher par criblage des agents modulant l'activité de MSREBP.
Bibliography:Application Number: WO2002US32807