METHOD FOR PRODUCING PROTEIN LIBRARIES AND FOR SELECTING PROTEINS FROM SAID LIBRARIES

• Main Authors: POUSTKA, ANNEMARIE, BREITLING, FRANK, KUEHLWEIN, THORSTEN, LUETTGAU, SANDRA, MOLDENHAUER, GERHARD
• Format: Patent
• Language: English; French; German
• Published: 11.12.2003
• Edition: 7
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMBINATORIAL CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

Beschrieben wird ein Verfahren zur Herstellung einer Protein-Bibliothek, insbesondere einer Antikörper-Bibliothek, mit hoher Diversität und zur Selektion von Proteinen, insbesondere Antikörpern, daraus. The invention relates to a method for producing a highly diverse protein library, in particular an antibody library and for selecting proteins, in particular antibodies, from said library. L'invention concerne un procédé permettant de produire une banque de protéines, en particulier une banque d'anticorps, présentant une grande diversité et sélectionner des protéines, en particulier des anticorps, à partir de cette banque.