NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME

A method for preparing a nitric oxide-releasing substrate that includes contacting an amine-functionalized silane with a substrate, contacting at least one additional amine-functionalized silane with the substrate, and contacting the substrate with nitric oxide, and repeating these steps if and as d...

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Bibliographic Details
Main Authors CHENG, PEIWEN, FITZHUGH, ANTHONY
Format Patent
LanguageEnglish
French
Published 03.04.2003
Edition7
Subjects
CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES
DISINFECTION, STERILISATION, OR DEODORISATION OF AIR
HUMAN NECESSITIES
HYGIENE
MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES
MEDICAL OR VETERINARY SCIENCE
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:A method for preparing a nitric oxide-releasing substrate that includes contacting an amine-functionalized silane with a substrate, contacting at least one additional amine-functionalized silane with the substrate, and contacting the substrate with nitric oxide, and repeating these steps if and as desired to produce a coating of the desired thickness as well as quantity and duration of nitric oxide-release. L'invention concerne un procédé de préparation d'un substrat à libération d'oxyde nitrique consistant à mettre un silane à fonction amine en contact avec un substrat, à mettre au moins un silane à fonction amine additionnel en contact avec ce substrat, et à mettre ledit substrat en contact avec de l'oxyde nitrique, puis à répéter ces opérations, si nécessaire, de manière à produire un revêtement d'épaisseur souhaitée libérant de l'oxyde nitrique en quantité suffisante pendant une durée appropriée.
Bibliography:Application Number: WO2002US30160