THERAPEUTIC POLYPEPTIDES, NUCLEIC ACIDS ENCODING SAME, AND METHODS OF USE

• Main Authors: LEPLEY, DENISE, M, GERLACH, VALERIE, L, EDINGER, SHLOMIT, R, ZHONG, MEI, PENA, CAROL, E., A, ALSOBROOK, JOHN, P., II, BURGESS, CATHERINE, E, SHIMKETS, RICHARD, A, SPYTEK, KIMBERLY, A, RIEGER, DANIEL, K, TAUPIER, RAYMOND, J., JR, PATTURAJAN, MEERA
• Format: Patent
• Language: English; French
• Published: 20.03.2003
• Edition: 7
• Subjects: AGRICULTURE; ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; CHEMISTRY; FISHING; FORESTRY; HUMAN NECESSITIES; HUNTING; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; NEW BREEDS OF ANIMALS; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; TRAPPING

Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins. La présente invention concerne des séquences d'acide nucléique qui codent de nouveaux polypeptides, les polypeptides codés par ces séquences d'acide nucléique et des anticorps qui se lient de manière immunospécifique au polypeptide, ainsi que des dérivés, des variants, des mutants ou des fragments du nouveau polypeptide, du polynucléotide ou de l'anticorps spécifique dudit polypeptide. Cette invention concerne également des méthodes de thérapie, de diagnostic et de recherche qui permettent de diagnostiquer, de traiter et de prévenir les troubles dans lesquels est impliqué un de ces nouveaux acides nucléiques humains ou une de ces nouvelles protéines humaines.