METHOD FOR CREATING A CELL GROWTH SURFACE ON A POLYMERIC SUBSTRATE

• Main Authors: SHEN, ZHONG-HE, BRYHAN, MARIE, D, LACHANCE, OLIVA, V, WANG, HONGMING, GAGNON, PETER, E
• Format: Patent
• Language: English; French
• Published: 13.03.2003
• Edition: 7
• Subjects: AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F,C08G; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING; APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPLYING LIQUIDS OR OTHER FLUENT MATERIALS TO SURFACES, IN GENERAL; BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS BASED THEREON; ENZYMOLOGY; GENERAL PROCESSES OF COMPOUNDING; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; ORGANIC MACROMOLECULAR COMPOUNDS; PERFORMING OPERATIONS; PROCESSES FOR APPLYING LIQUIDS OR OTHER FLUENT MATERIALS TOSURFACES, IN GENERAL; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDEDFOR; SHAPING OR JOINING OF PLASTICS; SPIRITS; SPRAYING OR ATOMISING IN GENERAL; THEIR PREPARATION OR CHEMICAL WORKING-UP; TRANSPORTING; VINEGAR; WINE; WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE, IN GENERAL; WORKING-UP

A method, apparatus and product for producing an advantaged cell growth surface. According to the present invention, a stream of plasma is comprised of activated gaseous species generated by a microwave source (10). This stream is directed at the surface of a polymer substrate (26) in a controlled fashion such that the surface is imparted with attributes for cell adhesion far superior to that of untreated polymer or polymer treated by other known methods. L'invention concerne un procédé, un appareil et un produit permettant de produire une surface de croissance cellulaire avantageuse. Selon l'invention, un flux de plasma est constitué d'espèces gazeuses activées, produites par une source micro-ondes (10). Ce flux est dirigé sur la surface d'un substrat polymère (26), de manière régulée, de sorte à conférer à ladite surface des propriétés d'adhérence des cellules nettement supérieures à celles d'un polymère non traité ou traité selon d'autres procédés connus.