NOVEL HUMAN PROTEINS, POLYNUCLEOTIDES ENCODING THEM AND METHODS OF USING THE SAME

• Main Authors: HJALT, TORD, GERLACH, VALERIE, L, ZERHUSEN, BRYAN, D, EDINGER, SHLOMIT, R, MALYANKAR, URIEL, M, ZHONG, MEI, SHIMKETS, RICHARD, A, SHENOY, SURESH, G, PATTURAJAN, MEERA, GUO, XIAOJIA, CASMAN, STACIE, J, ANDERSON, DAVID, W, GORMAN, LINDA, LI, LI, PADIGARU, MURALIDHARA, TAUPIER, RAYMOND, J., JR, MILLER, CHARLES, E, KEKUDA, RAMESH
• Format: Patent
• Language: English; French
• Published: 08.05.2003
• Edition: 7
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; DERIVATIVES THEREOF; ENZYMOLOGY; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; NUCLEIC ACIDS; NUCLEOSIDES; NUCLEOTIDES; ORGANIC CHEMISTRY; PEPTIDES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; SUGARS; VINEGAR; WINE

Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins. L'invention concerne des séquences d'acides nucléiques codant pour des nouveaux polypeptides. L'invention concerne également des polypeptides codés par ces séquences d'acides nucléiques, et des anticorps se fixant de manière immunospécifique au polypeptide, ainsi que des dérivés, des variants, des mutants ou des fragments du nouveau polypeptide, du nouveau polynucléotide, ou du nouvel anticorps propre au polypeptide. Cette invention concerne également des vecteurs, des cellules hôtes, des anticorps et des méthodes de recombinaison permettant de produire les polypeptides et les polynucléotides, ainsi que des procédés permettant de les utiliser. L'invention concerne également des méthodes thérapeutiques, diagnostiques et de recherche permettant le traitement, le diagnostic et la prévention de troubles impliquant n'importe lesquels des nouveaux acides nucléiques humains et protéines humaines.