AMORPHOUS COMPOUND

The present invention relates to a novel form of (S)-1-[N2-(1-carboxy-3-phenylpropyl)-L-lysyl]-L-proline known under the generic name lisinopril. Further, the present invention also relates to the use of the novel amorphous form of lisinopril for the treatment of hypertension and other cardiovascula...

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Bibliographic Details
Main Authors BROWN, JOHN, ROBERTS, RONALD, JOHN
Format Patent
LanguageEnglish
French
Published 03.01.2003
Edition7
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention relates to a novel form of (S)-1-[N2-(1-carboxy-3-phenylpropyl)-L-lysyl]-L-proline known under the generic name lisinopril. Further, the present invention also relates to the use of the novel amorphous form of lisinopril for the treatment of hypertension and other cardiovascular diseases, pharmaceutical compositions containing it as well as processes for the preparation of the novel amorphous form of lisinopril. La présente invention concerne une nouvelle forme de (S)-1-[N -(1-carboxy-3-phénylpropyle)-L-lysyle]-L-proline connue sous le nom générique de lisinopril. De plus, la présente invention concerne également l'utilisation de la nouvelle forme amorphe de lisinopril pour le traitement de l'hypertension et d'autres maladies cardiovasculaires, des compositions pharmaceutiques la contenant ainsi que des procédés de préparation de la nouvelle forme amorphe de lisinopril.
Bibliography:Application Number: WO2002GB02850