ONCOLYTIC VIRUS

Methods of reducing the viability of a tumor cell, infecting a neoplasm in a mammal with a virus, or treating a neoplasm in a mammal, utilizing certain non-naturally occuring viruses are disclosed. Viral reassortants, for example reovirus reassortants, and techniques for identifying PKR-sensitive vi...

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Bibliographic Details
Main Authors BELL, JOHN, CAMERON, BROWN, EARL, GARNET
Format Patent
LanguageEnglish
French
Published 28.11.2002
Edition7
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:Methods of reducing the viability of a tumor cell, infecting a neoplasm in a mammal with a virus, or treating a neoplasm in a mammal, utilizing certain non-naturally occuring viruses are disclosed. Viral reassortants, for example reovirus reassortants, and techniques for identifying PKR-sensitive viruses are also disclosed. L'invention concerne des procédés servant à limiter la viabilité d'une cellule cancéreuse, à infecter une tumeur par un virus chez un mammifère ou à traiter une tumeur chez un mammifère au moyen de certains virus artificiels. Elle concerne également des virus réassortis, par exemple, des réovirus réassortis, ainsi que des techniques servant à identifier des virus sensibles à PKR.
Bibliography:Application Number: WO2001US45108