METHOD OF ELIMINATING HUMAN SERUM ALBUMIN POLYMERS

A method of eliminating human serum albumin polymers characterized by bringing a human serum albumin solution containing human serum albumin polymers into contact with an anion exchanger having been equilibrated with a buffer solution which has a salt concentration of 10 to 150 mM and a pH value of...

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Main Authors NOUCHI, TOSHINOBU, MIYATSU, YOSHINOBU, USHIO, YOSHITAKA, MIZOKAMI, HIROSHI, ADACHI, SATOSHI, TAJIMA, YOSHITAKA
Format Patent
LanguageEnglish
French
Japanese
Published 02.05.2002
Edition7
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A method of eliminating human serum albumin polymers characterized by bringing a human serum albumin solution containing human serum albumin polymers into contact with an anion exchanger having been equilibrated with a buffer solution which has a salt concentration of 10 to 150 mM and a pH value of 5 to 9.5. Ce procédé d'élimination de polymères d'albumine sérique humaine consiste à mettre en contact une solution d'albumine sérique humaine contenant des polymères d'albumine sérique humaine, avec un échangeur d'anions équilibré au moyen d'une solution tampon dont la teneur en sel est comprise entre 10 et 150 mM et la valeur du pH comprise entre 5 et 9,5.
Bibliography:Application Number: WO2001JP09335