NOVEL PROTEINS AND NUCLEIC ACIDS ENCODING SAME

• Main Authors: ZHONG, MEI, ANDERSON, DAVID, W, GUSEV, VLADIMIR, Y, LI, LI, PENA, CAROL, E., A, HERRMANN, JOHN, L, SPADERNA, STEVEN, K, MEZES, PETER, S, GUO, XIAOJIA
• Format: Patent
• Language: English; French
• Published: 24.12.2003
• Edition: 7
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving anyone of these novel human nucleic acids and proteins. L'invention concerne des séquences d'acides nucléiques codant pour des polypeptides associés à un récepteur couplé aux protéines G. Elle concerne aussi des polypeptides codés par ces séquences d'acides nucléiques, des anticorps qui se lient de façon immunospécifique à ces polypeptides, ainsi que des dérivés, variants, mutants ou fragments des ces polypeptides, polynucléotides ou anticorps. Elle concerne enfin des procédés thérapeutiques, de diagnostic, de traitement et de prévention de troubles impliquant l'un de ces acides nucléiques et protéines.