PHARMACEUTICAL COMPOSITIONS CONTAINING TOBRAMYCIN AND XANTHAN GUM

Topically administrable aqueous solution compositions containing tobramycin and xanthan gum are disclosed. The solution compositions contain a buffering agent and a pH-adjusting agent in an amount sufficient to achieve a pH above 7.8 in order to minimize or avoid compatibility problems between tobra...

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Bibliographic Details
Main Authors TORRELLA CABELLO, GEMMA, VALLET MAS, JOSE ALBERTO, CARRERAS PERDIGUER, NURIA
Format Patent
LanguageEnglish
French
Published 07.02.2002
Edition7
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Topically administrable aqueous solution compositions containing tobramycin and xanthan gum are disclosed. The solution compositions contain a buffering agent and a pH-adjusting agent in an amount sufficient to achieve a pH above 7.8 in order to minimize or avoid compatibility problems between tobramycin and xanthan gum. Compositions sous forme de solutions aqueuses pour administration locale, qui contiennent un tampon et un agent de régulation du pH en quantité suffisante pour obtenir un pH supérieur à 7,8, ce qui permet de réduire à un minimum, voire d'éviter, les problèmes de compatibilité entre la tobramycine et la gomme de xanthane.
Bibliography:Application Number: WO2001EP07267