GPE ANALOGS AND PEPTIDOMIMETICS

The invention relates to analogs and peptidomimetics of glycyl-L-prolyl-L-glutamic acid (GPE). In particular, this invention relates to GPE analogs and peptidomimetics that are anti-apoptotic and anti-necrotic, to methods of making them, to pharmaceutical compositions containing them, and to their u...

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Bibliographic Details
Main Authors BRIMBLE, MARGARET, ANNE, ABOOD, NORMAN, A
Format Patent
LanguageEnglish
French
Published 15.05.2003
Edition7
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to analogs and peptidomimetics of glycyl-L-prolyl-L-glutamic acid (GPE). In particular, this invention relates to GPE analogs and peptidomimetics that are anti-apoptotic and anti-necrotic, to methods of making them, to pharmaceutical compositions containing them, and to their use. L'invention concerne des peptidomimétiques et des analogues d'acide glycyl-L-prolyl-L-glutamique (GPE). L'invention porte notamment sur des peptidomimétiques et sur des analogues de GPE qui sont anti-apoptotiques et anti-nécrotiques, sur leurs procédés de fabrication, sur des préparations pharmaceutiques les contenant et sur leur utilisation.
Bibliography:Application Number: WO2002US16361