THERAPEUTIC POLYPEPTIDES, NUCLEIC ACIDS ENCODING SAME, AND METHODS OF USE

Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the-polypeptide, as well as derivatives, variants, mutants, or fragments...

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Main Authors EDINGER, SCHLOMIT, R, GERLACH, VALERIE, L, CASMAN, STACIE, J, ANDERSON, DAVID, W, ELLERMAN, KAREN, GORMAN, LINDA, ALSOBROOK, JOHN, P., II, BURGESS, CATHERINE, E, GANGOLLI, ESHA, A, BOLDOG, FERENC, L
Format Patent
LanguageEnglish
French
Published 21.04.2005
Edition7
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Summary:Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the-polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins. L'invention concerne des séquences d'acide nucléique codant des polypeptides associés au récepteur couplé à la protéine G. L'invention concerne également des polypeptides codés par lesdites séquences d'acide nucléique, des anticorps qui se lient au polypeptide de façon immunospécifique, ainsi que des dérivés, variants, mutants, ou des fragments du polypeptide, polynucléotide, ou anticorps concernés. L'invention se rapporte en outre à des méthodes thérapeutiques, des méthodes diagnostiques et des méthodes de recherche permettant de diagnostiquer, traiter et prévenir des troubles impliquant un(e) quelconque de ces protéines et acides nucléiques humains.
Bibliography:Application Number: WO2002US14341