MATURATION OF ANTIGEN-PRESENTING CELLS USING ACTIVATED T CELLS

The present invention relates to methods for maturing antigen-presenting cells, and more particularly, to methods for maturing antigen-presenting cells. Methods for generating mature and/or maturing antigen-presenting cells in vitro and in vivo are disclosed. The present invention also relates to co...

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Main Authors BERENSON, RONALD, JAY, KALAMASZ, DALE, MONJI, TATSUE, BONYHADI, MARK, CRAIG, STEWART
Format Patent
LanguageEnglish
French
Published 07.11.2002
Edition7
Subjects
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Summary:The present invention relates to methods for maturing antigen-presenting cells, and more particularly, to methods for maturing antigen-presenting cells. Methods for generating mature and/or maturing antigen-presenting cells in vitro and in vivo are disclosed. The present invention also relates to compositions of cells, including mature antigen-presenting cells and/or activated T cells and their use in generating immune responses in vivo, and inhibiting the development of or preventing infectious diseases and cancers. La présente invention concerne des procédés destinés à la maturation des cellules présentatrices des antigènes et notamment des procédés pour porter à maturation des cellules présentatrices des antigènes. L'invention concerne des procédés pour générer des cellules matures et/ou de porter à maturation des cellules présentatrices des antigènes. L'invention concerne aussi des compositions de cellules, y compris des cellules matures présentant des antigènes et/ou des lymphocytes T activés et leur utilisant dans la génération de réponses immunes in vivo, y compris l'inhibition du développement des maladies infectieuses et des cancers ou la prévention de ces maladies.
Bibliography:Application Number: WO2002US13616