METHOD AND DEVICE FOR DETERMINING AND SELECTING MOLECULE-MOLECULE INTERACTIONS

• Main Authors: GILLNER, ARNOLD, BARTH, STEFAN, BREMUS-KOEBBERLING, ELKE, FISCHER, RAINER
• Format: Patent
• Language: English; French; German
• Published: 20.11.2003
• Edition: 7
• Subjects: APPARATUS THEREFOR; BEER; BIOCHEMISTRY; CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY; CHEMISTRY; COMBINATORIAL CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; GENERAL METHODS OF ORGANIC CHEMISTRY; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES; MEASURING; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; PHYSICS; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; TESTING; THEIR RELEVANT APPARATUS; TRANSPORTING; VINEGAR; WINE

Verfahren und Vorrichtung zur Bestimmung und Selektion von Molekül-Molekül-Wechselwirkungen. Die vorliegende Erfindung betrifft Biochips zur Dokumentation spezifischer Molekül-Molekül-Wechselwirkungen bzw. Zell-Molekül-Wechselwirkungen, insbesondere von unbekannten, singulären Protein-Interaktionen und entsprechende Verfahren zur Selektion und Charakterisierung von Molekülen, insbesondere Polypeptiden und ihren komplementären Bindungsmolekülen. The invention relates to biochips for documenting specific molecule-molecule interactions or cell-molecule interactions, more particularly unknown singular protein interactions. The invention also relates to corresponding methods for selecting and characterizing molecules, especially polypeptides and the complementary binding molecules. L'invention concerne des biopuces destinées à la documentation d'interactions molécule-molécule spécifiques ou d'interactions cellule-molécule, notamment d'interactions de protéines singulières inconnues. L'invention concerne également les procédés correspondants de sélection et de caractérisation de molécules, notamment de polypeptides et leurs molécules de liaison complémentaires.