GROWTH FACTOR POLYPEPTIDES AND NUCLEIC ACIDS ENCODING SAME

Disclosed are novel nucleic acids encoding proteins and polypeptides related to bone morphogenetic protein-1 (BMF1) and to vascular endothelial growth factor E (VEGF-E) and platelet derived growth factor (PDGF). Also disclosed are vectors, host cells, antibodies, and recombinant methods for producin...

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Bibliographic Details
Main Authors LICHENSTEIN, HENRI, JEFFERS, MICHAEL, ANDREWS, DAVID, SHIMKETS, RICHARD, A, LAROCHELLE, WILIAM, HERRMANN, JOHN, L, BOLDOG, FERENC, L, MINSKOFF, STACEY
Format Patent
LanguageEnglish
French
Published 01.08.2002
Edition7
Subjects
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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Summary:Disclosed are novel nucleic acids encoding proteins and polypeptides related to bone morphogenetic protein-1 (BMF1) and to vascular endothelial growth factor E (VEGF-E) and platelet derived growth factor (PDGF). Also disclosed are vectors, host cells, antibodies, and recombinant methods for producing these nucleic acids and polypeptides. Methods of use include detecting and staging of cancers. La présente invention concerne des nouveaux acides nucléiques codant pour des protéines et des polypeptides associés à la protéine morphogénétique osseuse-1 (BMP1) et au facteur de croissance endothélial vasculaire E (VEGF-E), ainsi qu'au facteur de croissance plaquettaire (PDGF). L'invention concerne également des vecteurs, des cellules hôtes, des anticorps, et des méthodes de recombinaison permettant de produire ces acides nucléiques et ces polypeptides. Les méthodes d'utilisation consistent à détecter et à établir le stade des cancers.
Bibliography:Application Number: WO2001US48901