THERMOSTABLE CELLULASE

Disclosed are variant thermostable cellulases, nucleic acids encoding the variants and methods for producing the variants. The variant thermostable cellulases have the amino acid sequence of a glycosyl hydrolase of family 12 wherein one or more amino acid residues which are not part of the catalytic...

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Main Authors WICHER, KRYZYSZTOF, B, HOLST, OLOF, PEDER, KARLSSON, EVA, MARGARETA, NORDBERG, HA, MAHER, YOUSSEF, ABOU, HREGGVIDSSON, GUDMUNDUR, O
Format Patent
LanguageEnglish
French
Published 20.12.2001
Edition7
Subjects
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Summary:Disclosed are variant thermostable cellulases, nucleic acids encoding the variants and methods for producing the variants. The variant thermostable cellulases have the amino acid sequence of a glycosyl hydrolase of family 12 wherein one or more amino acid residues which are not part of the catalytic domain are deleted. In specific embodiments, the variant thermostable cellulase is a variant of Cell2A of Rhodothermus marinus. L'invention concerne des variantes de cellulases thermostables, des acides nucléiques codant pour ces variantes et des procédés pour produire ces variantes. Les variantes de cellulases thermostables comportent une séquence d'acides aminés d'une glycosyle hydrolase de la famille 12 dans laquelle on a enlevé un ou plusieurs résidus d'acides aminés ne faisant pas partie du domaine catalytique. Dans des modes de réalisation déterminés, la variante de cellulase thermostable est une variante de Cel12A de Rhodothermus marinus.
Bibliography:Application Number: WO2001IS00012