CYCLOALKYL ALKANOIC ACIDS AS INTEGRIN RECEPTOR ANTAGONISTS

The present invention relates to a class of compounds represented by the Formula (I) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula (I), and methods of selectively inhibiting or antagonizing the alpha nu beta 3 and/or alpha nu beta 5 in...

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Bibliographic Details
Main Authors CHEN, BARBARA, RUSSEL, MARK, ROGERS, THOMAS, GASIECKI, ALAN, F, KHANNA, ISH, KUMAR, HWANG-FUN, LU, CLARE, MICHAEL
Format Patent
LanguageEnglish
French
Published 20.12.2001
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to a class of compounds represented by the Formula (I) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula (I), and methods of selectively inhibiting or antagonizing the alpha nu beta 3 and/or alpha nu beta 5 integrin. L'invention concerne une classe de composés représentés par la formule I ou un sel pharmaceutiquement acceptable de ceux-ci, des compositions pharmaceutiques contenant les composés représentés par la formule I, et des procédés d'inhibition ou d'antagonisation sélective de l'intégrine alpha V beta 3 et/ou alpha V beta 5.
Bibliography:Application Number: WO2001US19104