NOVEL HUMAN POLYNUCLEOTIDES AND POLYPEPTIDES ENCODED THEREBY

• Main Authors: SHIMKETS, RICHARD, A, LEACH, MARTIN, D
• Format: Patent
• Language: English; French
• Published: 06.12.2001
• Edition: 7
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

The present invention provides ORFX, a novel isolated polypeptide, as well as a polynucleotide encoding ORFX and antibodies that immunospecifically bind to ORFX or any derivative, variant, mutant, or fragment of the ORFX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the ORFX polypeptide, polynucleotide and antibody are used in detection and treatment of a broad range of pathological states, as well as to other uses. La présente invention concerne le polypeptide ORFX, nouveau polypeptide isolé, ainsi qu'un polynucléotide codant pour le polypeptide ORFX et des anticorps qui se fixent de façon immunospécifique à ORFX ou à n'importe quel dérivé, variant, mutant ou fragment de ce polypeptide ORFX, de ce polynucléotide ou de cet anticorps. Cette invention concerne aussi des techniques dans lesquelles le polypeptide ORFX, le polynucléotide et l'anticorps sont utilisés pour détecter et traiter un grand nombre d'états pathologiques, ainsi que d'autres utilisations.