G-PROTEIN COUPLED RECEPTOR RELATED POLYPEPTIDES

• Main Authors: LI, LI, BAUMGARTNER, JASON, C, BURGESS, CATHERINE, E, SPYTEK, KIMBERLY, A, MISHRA, VISHNU, S, PADIGARU, MURALIDHARA, MAJUMDER, KUMUD, TCHERNEV, VELIZAR, T
• Format: Patent
• Language: English; French
• Published: 30.05.2002
• Edition: 7
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPOSITIONS THEREOF; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; CULTURE MEDIA; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; HUMAN NECESSITIES; HYGIENE; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PHYSICS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROCESSES OF PREPARING SUCH COMPOSITIONS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; TESTING; VINEGAR; WINE

Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecificlly-bind o the polypeptide, as well as derivatives, variants, mutants, or fragments or the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins. L'invention se rapporte à des séquences d'acides nucléiques qui codent pour des polypeptides associés à des récepteurs-protéines couplés à une protéine G. L'invention se rapporte à des polypeptides codés par ces séquences d'acides nucléiques, et à des anticorps qui se lient de manière immuno-spécifique audit polypeptide, ainsi qu'à des dérivés, variants, mutants ou fragments du polypeptide, polynucléotide ou anticorps ci-dessus mentionné. L'invention se rapporte en outre à des méthodes thérapeutiques, diagnostiques et de recherche permettant le traitement, le diagnostic et la prévention de troubles impliquant n'importe lequel de ces nouveaux acides nucléiques ou n'importe laquelle de ces nouvelles protéines d'origine humaine.